Article
Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia.
Journal of cancer research and clinical oncology - 1 Dec 2015
Junghanns Anne-Sophie, Wittig Susan, Woehlecke Caroline, Lehmann Thomas, Arndt Clemens, Gruhn Bernd
Abstract excerpt
PURPOSE: Wilms tumor gene single nucleotide polymorphism (WT1 SNP) rs16754 has been described as a favorable risk marker in patients with acute myeloid leukemia. Subsequent studies revealed inconsistent results in both adult and pediatric patients. We analyzed its impact on clinical outcome in children with acute lymphoblastic leukemia (ALL) for the first time. METHODS: WT1 SNP rs16754 of 158 children with ALL...
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