Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment

24 Dec 2015

Abstract excerpt

B cells are key components of cellular and humoral immunity and, like all lymphocytes, are thought to originate and renew from hematopoietic stem cells (HSCs). However, our recent single-HSC transfer studies demonstrate that adult bone marrow HSCs do not regenerate B-1a, a subset of tissue B cells required for protection against pneumonia, influenza, and other infections. Since B-1a are regenerated by transfers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Neonatal Respiratory Health Research
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26724903
DOI: 10.1016/j.stemcr.2015.11.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte CompartmentPMID 26724903Read ↗

Ontogeny of human B1 cells.Semantic proximity Read ↗

Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cellsSemantic proximity Read ↗

Lymphoid cell development from fetal hematopoietic progenitors and human pluripotent stem cellsSemantic proximity Read ↗

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseasesSemantic proximity Read ↗

Embryonic hematopoiesis.Semantic proximity Read ↗

Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source.Semantic proximity Read ↗

Fetal and adult progenitors give rise to unique populations of CD8+ T cells.Semantic proximity Read ↗

Identification of the minimum requirements for successful haematopoietic stem cell transplantation.Semantic proximity Read ↗

Human B-1 cells take the stage.Semantic proximity Read ↗

Fetal origins of hematopoietic failure in a murine model of Fanconi anemiaSemantic proximity Read ↗

Circulating hematopoietic progenitors with T lineage potential.Semantic proximity Read ↗

A developmental switch in B lymphopoiesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.