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Article

Human B-1 cells take the stage.

Annals of the New York Academy of Sciences - 1 May 2013

Rothstein Thomas L, Griffin Daniel O, Holodick Nichol E, Quach Tam D, Kaku Hiroaki

Abstract excerpt

B-1 cells play critical roles in defending against microbial invasion and in housekeeping removal of cellular debris. B-1 cells secrete natural antibody and manifest functions that influence T cell expansion and differentiation and in these and other ways differ from conventional B-2 cells. B-1 cells were originally studied in mice where they are easily distinguished from B-2 cells, but their identity in the...

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Identifiers

PMID: 23692567
DOI: 10.1111/nyas.12137
PMCID: PMC4429725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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