Article
A developmental switch in B lymphopoiesis.
Proceedings of the National Academy of Sciences of the United States of America - 15 Dec 1991
Hardy R R, Hayakawa K
Abstract excerpt
B and T lymphocytes are generated from hematopoietic stem cells during both fetal and adult life. A critical unresolved issue is whether the differentiation pathways in lymphopoiesis are the same in fetal and adult animals or whether they differ, similar to the hemoglobin switch in erythropoiesis...
Topics
- Aging
- Animals
- Antigens, CD
- B-Lymphocytes
- Bone Marrow
- CD5 Antigens
- Embryonic and Fetal Development
- Flow Cytometry
- Gene Rearrangement
- Genes, Immunoglobulin
- Immunoglobulin D
- Liver
- Mice
- Mice, Inbred BALB C
- Phenotype
- Polymerase Chain Reaction