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Lymphoid cell development from fetal hematopoietic progenitors and human pluripotent stem cells

20 Mar 2023

Abstract excerpt

Lymphoid cells encompass the adaptive immune system, including T and B cells and Natural killer T cells (NKT), and innate immune cells (ILCs), including Natural Killer (NK) cells. During adult life, these lineages are thought to derive from the differentiation of long-term hematopoietic stem cells (HSCs) residing in the bone marrow. However, during embryogenesis and fetal development, the ontogeny of lymphoid...

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PMID: 36939073
DOI: 10.1111/imr.13197

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