Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ancestral-derived effects on the mutational landscape of laryngeal cancer.

Genomics - 1 Mar 2016

Ramakodi Meganathan P, Kulathinal Rob J, Chung Yujin, Serebriiskii Ilya, Liu Jeffrey C, Ragin Camille C

Abstract excerpt

Laryngeal cancer disproportionately affects more African-Americans than European-Americans. Here, we analyze the genome-wide somatic point mutations from the tumors of 13 African-Americans and 57 European-Americans from TCGA to differentiate between environmental and ancestrally-inherited factors. The mean number of mutations was different between African-Americans (151.31) and European-Americans (277.63). Other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Gene Frequency
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Laryngeal Neoplasms

Share to Point Mutation

Share to United States

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 26721311
DOI: 10.1016/j.ygeno.2015.12.004
PMCID: PMC4761303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ancestral-derived effects on the mutational landscape of laryngeal cancer.PMID 26721311Read ↗

Ancestry-, Sex-, and Age-Based Differences of Gene Alterations in NSCLC: From the Real-World Data of Cancer Genomic Profiling Tests.Semantic proximity Read ↗

Genetic determinants in head and neck squamous cell carcinoma and their influence on global personalized medicineSemantic proximity Read ↗

Molecular Subtypes of Head and Neck Cancer in Patients of African Ancestry.Semantic proximity Read ↗

Somatic mosaicism in the buccal mucosa reflects lifestyle and germline risk factors for esophageal squamous cell carcinomaSemantic proximity Read ↗

Genetic Ancestry Correlations with Driver Mutations Suggest Complex Interactions between Somatic and Germline Variation in Cancer.Semantic proximity Read ↗

Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapySemantic proximity Read ↗

Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populationsSemantic proximity Read ↗

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patients.Semantic proximity Read ↗

Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations.Semantic proximity Read ↗

Effect of actionable somatic mutations on racial/ethnic disparities in head and neck cancer prognosis.Semantic proximity Read ↗

The impact of genomic ancestry on tumor genomics in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase β and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.