Article
Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patients.
Scientific reports - 18 Apr 2024
Lim Hyeyeun, Gingras Marie-Claude, Zhao Jing, Byun Jinyoung, Castro Patricia D, Tsavachidis Spiridon, Hu Jianhong, Doddapaneni Harshavardhan, Han Yi, Muzny Donna M, Gibbs Richard A, Amos Christopher I, Thrift Aaron P
Abstract excerpt
Esophageal adenocarcinoma is the most common histological subtype of esophageal cancer in Western countries and shows poor prognosis with rapid growth. EAC is characterized by a strong male predominance and racial disparity. EAC is up to fivefold more common among Whites than Blacks, yet Black patients with EAC have poorer survival rates. The racial disparity remains largely unknown, and there is limited...
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