Article
Effect of actionable somatic mutations on racial/ethnic disparities in head and neck cancer prognosis.
Head & neck - 1 Aug 2016
Wu Evan S, Park Jong Y, Zeitouni Joseph A, Gomez Carmen R, Reis Isildinha M, Zhao Wei, Kwon Deukwoo, Lee Eunkyung, Nelson Omar L, Lin Hui-Yi, Franzmann Elizabeth J, Savell Jason, McCaffrey Thomas V, Goodwin W Jarrard, Hu Jennifer J
Abstract excerpt
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and minorities have the worst survival. However, the molecular mechanisms underlying survival disparities have not been elucidated. METHODS: In a retrospective study, we assessed association between HNSCC early death (<2 years) and 208 somatic mutations of 10 cancer-related genes in 214 patients: 98 non-Hispanic...
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