Article
Structural Motifs Critical for In Vivo Function and Stability of the RecQ-Mediated Genome Instability Protein Rmi1.
PloS one - 1 Jan 2015
Kennedy Jessica A, Syed Salahuddin, Schmidt Kristina H
Abstract excerpt
Rmi1 is a member of the Sgs1/Top3/Rmi1 (STR) complex of Saccharomyces cerevisiae and has been implicated in binding and catalytic enhancement of Top3 in the dissolution of double Holliday junctions. Deletion of RMI1 results in a severe growth defect resembling that of top3Δ. Despite the importance of Rmi1 for cell viability, little is known about its functional domains, particularly in Rmi1 of S. cerevisiae,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
