Article
Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes.
Schizophrenia bulletin - 1 Jul 2016
Voineskos Aristotle N, Felsky Daniel, Wheeler Anne L, Rotenberg David J, Levesque Melissa, Patel Sejal, Szeszko Philip R, Kennedy James L, Lencz Todd, Malhotra Anil K
Abstract excerpt
BACKGROUND: There are now over 100 established genetic risk variants for schizophrenia; however, their influence on brain structure and circuitry across the human lifespan are not known. METHODS: We examined healthy individuals 8-86 years of age, from the Centre for Addiction and Mental Health, the Zucker Hillside Hospital, and the Philadelphia Neurodevelopmental Cohort. Following thorough quality control...
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