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Article

An investigation of a genomewide supported psychosis variant in ZNF804A and white matter integrity in the human brain.

Magnetic resonance imaging - 1 Dec 2012

Sprooten Emma, McIntosh Andrew M, Lawrie Stephen M, Hall Jeremy, Sussmann Jess E, Dahmen Norbert, Konrad Andreas, Bastin Mark E, Winterer Georg

Abstract excerpt

ZNF804A, a genomewide supported susceptibility gene for schizophrenia and bipolar disorder, has been associated with task-independent functional connectivity between the left and right dorsolateral prefrontal cortices. Several lines of evidence have converged on the hypothesis that this effect may be mediated by structural connectivity. We tested this hypothesis using diffusion tensor magnetic resonance imaging...

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Identifiers

PMID: 22840435
DOI: 10.1016/j.mri.2012.05.013
PMCID: PMC3778890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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An investigation of a genomewide supported psychosis variant in ZNF804A and white matter integrity in the human brain.PMID 22840435Read ↗

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Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorderSemantic proximity Read ↗

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The ZNF804A gene: characterization of a novel neural risk mechanism for the major psychoses.Semantic proximity Read ↗

A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes.Semantic proximity Read ↗

Genome-wide supported psychosis risk variant in ZNF804A gene and impact on cortico-limbic WM integrity in schizophrenia.Semantic proximity Read ↗

Common variation in ZNF804A (rs1344706) is not associated with brain morphometry in schizophrenia or healthy participants.Semantic proximity Read ↗

ZNF804A genetic variation (rs1344706) affects brain grey but not white matter in schizophrenia and healthy subjects.Semantic proximity Read ↗

A schizophrenia risk gene, ZNF804A, is associated with brain white matter microstructure.Semantic proximity Read ↗

Neural mechanisms of a genome-wide supported psychosis variant.Semantic proximity Read ↗

Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes.Semantic proximity Read ↗

Partial support for ZNF804A genotype-dependent alterations in prefrontal connectivity.Semantic proximity Read ↗

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