Article
JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.
The Journal of biological chemistry - 26 Feb 2016
He Zhimin, Wu Junyu, Su Xiaonan, Zhang Ye, Pan Lixia, Wei Huimin, Fang Qiang, Li Haitao, Wang Da-Liang, Sun Fang-Lin
Abstract excerpt
Precise mitotic spindle assembly is a guarantee of proper chromosome segregation during mitosis. Chromosome instability caused by disturbed mitosis is one of the major features of various types of cancer. JMJD5 has been reported to be involved in epigenetic regulation of gene expression in the nucleus, but little is known about its function in mitotic process. Here we report the unexpected localization and...
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