Article
Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways
20 Apr 2011
Abstract excerpt
Various cytokines are involved in the regulation of the immune system and inflammation. Dysregulation of cytokine signaling can cause a variety of diseases, including allergy, autoimmune diseases, inflammation, and cancer. Most cytokines use the so-called janus kinase/signal transducer and activator of transcription pathway, and this pathway is negatively regulated by suppressors of cytokine signaling (SOCS)...
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