Article
A Pipeline for Classifying Relationships Using Dense SNP/SNV Data and Putative Pedigree Information.
Genetic epidemiology - 1 Feb 2016
Zeng Zhen, Weeks Daniel E, Chen Wei, Mukhopadhyay Nandita, Feingold Eleanor
Abstract excerpt
When genome-wide association studies (GWAS) or sequencing studies are performed on family-based datasets, the genotype data can be used to check the structure of putative pedigrees. Even in datasets of putatively unrelated people, close relationships can often be detected using dense single-nucleotide polymorphism/variant (SNP/SNV) data. A number of methods for finding relationships using dense genetic data...
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