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Article

Identity by descent between distant relatives: detection and applications.

Annual review of genetics - 1 Jan 2012

Browning Sharon R, Browning Brian L

Abstract excerpt

Short segments of identity by descent (IBD) between individuals with no known relationship can be detected using genome-wide single nucleotide polymorphism data and recently developed statistical methodology. Emerging applications for the detected IBD segments include IBD mapping, haplotype phase inference, genotype imputation, and inference of population structure. In this review, we explain the principles...

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PMID: 22994355
DOI: 10.1146/annurev-genet-110711-155534

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