Article
The Association of Flap Endonuclease 1 Genotypes with the Risk of Childhood Leukemia.
Cancer genomics & proteomics - 1 Jan 2000
Pei Jen-Sheng, Chang Wen-Shin, Hsu Pei-Chen, Tsai Chia-Wen, Hsu Chin-Mu, Ji Hong-Xue, Hsiao Chieh-Lun, Hsu Yuan-Nian, Bau Da-Tian
Abstract excerpt
AIM: Flap endonuclease 1 (FEN1) is one of the most important proteins in maintaining genome stability and preventing carcinogenesis. In recent years, the contribution of two variants of FEN1, rs174538 and rs4246215, regarding cancer risk have been investigated in lung, breast, liver, esophageal, gastric, colorectal cancer and glioma. However, it has not been revealed whether rs174538 and rs4246215 are associated...
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