Article
The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis.
Cancer genomics & proteomics - 1 Jan 2000
Chou An-Kuo, Shen Ming-Yi, Chen Fang-Yu, Hsiao Chieh-Lun, Shih Liang-Chun, Chang Wen-Shin, Tsai Chia-Wen, Ying Tsung-Ho, Wu Ming-Hsien, Huang Chung-Yu, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: Flap endonuclease 1 (FEN1), a protein with multiple functions in genome stability maintenance, is important in cancer prevention. The two functional germline variants of FEN1, rs174538 and rs4246215, regarding cancer susceptibility have been reported in lung, breast, liver, esophageal, gastric, colorectal cancer, glioma and leukemia, but not endometriosis. In this study, we firstly aimed at...
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