Article
New association between splicing factor-coding gene polymorphisms and the risk of acute lymphoblastic leukemia in southern Chinese children: A five-center case-control study.
The journal of gene medicine - 1 Apr 2023
Deng Decheng, Luo Ailing, Li Ming, Yan Yaping, Cai Mansi, Liu Shanshan, Liu Xiaodan, Wang Xueliang, Zhang Xiaohong, Jiang Hua, Liu Xiaoping
Abstract excerpt
BACKGROUND: The role of splicing factor-coding gene polymorphisms in pediatric acute lymphoblastic leukemia (ALL) susceptibility is still unclear. METHODS: A case-control designed model was used to estimate the overall risk of pediatric ALL and five single nucleotide polymorphisms (SNPs) of splicing factor-coding genes in 808 cases and 1,340 controls, which were genotyped using a TaqMan assay. Stratified analysis...
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