Impact of DNA Ligase 1 Genotypes on Childhood Acute Lymphocytic Leukemia.

doi:10.21873/invivo.13813

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Article

Impact of DNA Ligase 1 Genotypes on Childhood Acute Lymphocytic Leukemia.

In vivo (Athens, Greece) - 1 Jan 2000

Hsu Pei-Chen, Chen Chao-Chun, Tsai Hung-Wen, Chang Wen-Shin, Pei Jen-Sheng, Wang Yun-Chi, Lin Meng-Liang, He Jie-Long, Chen Shih-Shun, Tsai Chia-Wen, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Genetic polymorphisms in DNA repair mechanisms can modulate overall DNA repair capacity, potentially influencing individual susceptibility to cancer. This study investigated the relationship between polymorphic variations in DNA ligase 1 and the risk of childhood acute lymphocytic leukemia (cALL). MATERIALS AND METHODS: The genotypes of DNA ligase 1 rs20579 were determined using polymerase chain...

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PMID: 39740875
DOI: 10.21873/invivo.13813

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