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Precision methylome characterization of Mycobacterium tuberculosis complex (MTBC) using PacBio single-molecule real-time (SMRT) technology.

Nucleic acids research - 29 Jan 2016

Zhu Lingxiang, Zhong Jun, Jia Xinmiao, Liu Guan, Kang Yu, Dong Mengxing, Zhang Xiuli, Li Qian, Yue Liya, Li Cuidan, Fu Jing, Xiao Jingfa, Yan Jiangwei, Zhang Bing, Lei Meng, Chen Suting, Lv Lingna, Zhu Baoli, Huang Hairong, Chen Fei

Abstract excerpt

Tuberculosis (TB) remains one of the most common infectious diseases caused by Mycobacterium tuberculosis complex (MTBC). To panoramically analyze MTBC's genomic methylation, we completed the genomes of 12 MTBC strains (Mycobacterium bovis; M. bovis BCG; M. microti; M. africanum; M. tuberculosis H37Rv; H37Ra; and 6 M. tuberculosis clinical isolates) belonging to different lineages and characterized their...

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Identifiers

PMID: 26704977
DOI: 10.1093/nar/gkv1498
PMCID: PMC4737169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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