Article
Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain.
G3 (Bethesda, Md.) - 7 Jan 2020
Chhotaray Chiranjibi, Wang Shuai, Tan Yaoju, Ali Amjad, Shehroz Muhammad, Fang Cuiting, Liu Yang, Lu Zhili, Cai Xingshan, Hameed H M Adnan, Islam Md Mahmudul, Surineni Goverdhan, Tan Shouyong, Liu Jianxiong, Zhang Tianyu
Abstract excerpt
Mycobacterium abscessus is a fast growing Mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the genomes of two clinical M. abscessus strains having rough and smooth morphology, using the single molecule real-time and Illumina HiSeq sequencing technology. In...
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