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Deciphering a TB-related DNA methylation biomarker and constructing a TB diagnostic classifier

19 Nov 2021

Abstract excerpt

We systemically identified tuberculosis (TB)-related DNA methylation biomarkers and further constructed classifiers for TB diagnosis. TB-related DNA methylation datasets were searched through October 3, 2020. Limma and DMRcate were employed to identify differentially methylated probes (DMPs) and regions (DMRs). Machine learning methods were used to construct classifiers. The performance of the classifiers was...

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PMID: 34938605
DOI: 10.1016/j.omtn.2021.11.014

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