Article

Bilateral diffuse alveolar damage contributes to the fatal toxicity of pre-existing interstitial lung disease mice after partial thoracic irradiation

2024-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Lung cancer patients with comorbid interstitial lung disease (LC-ILD) have an increased risk of developing severe or even fatal radiation pneumonitis after thoracic radiotherapy. However, the underlying mechanisms of its pathogenesis are still inconclusive. No approved biomarker or medicine is available to prevent pulmonary toxicities in LC-ILD patients. Appropriate manageme...

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Literature Corpus work: 533051dd-3615-5a9a-9a1d-db912a796eed
DOI: 10.21203/rs.3.rs-4816003/v1

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