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Article

Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets

23 Dec 2015

Abstract excerpt

AIMS/HYPOTHESIS: Ageing is a major risk factor for development of metabolic diseases such as type 2 diabetes. Identification of the mechanisms underlying this association could help to elucidate the relationship between age-associated progressive loss of metabolic health and development of type 2 diabetes. We aimed to determine molecular signatures during ageing in the endocrine pancreas. METHODS: Global gene...

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Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology
Share to Pancreatic function and diabetes

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PMID: 26699651
DOI: 10.1007/s00125-015-3837-8

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