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Article

cfDNA analysis from blood in melanoma.

1 Nov 2015

Abstract excerpt

Testing of tumor tissue remains the recommended method for detecting the presence of somatic mutations in human malignancies. V600E is the most frequent somatic point mutation in metastatic melanoma, providing a unique molecular marker for this malignancy. In addition, tumors carrying this mutation are primary candidates for BRAF-targeted therapy. Although metastatic melanoma patients usually have sufficient...

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PMID: 26697469
DOI: 10.3978/j.issn.2305-5839.2015.11.23

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