Article
Evaluation of the liquid biopsy for the detection of BRAFV600E mutation in metastatic melanoma patients.
Cancer biomarkers : section A of Disease markers - 1 Jan 2019
Salvianti Francesca, Massi Daniela, De Giorgi Vincenzo, Gori Alessia, Pazzagli Mario, Pinzani Pamela
Abstract excerpt
BACKGROUND: Circulating tumor cells (CTCs) and circulating cell free DNA (ccfDNA) represent a liquid biopsy of a tumor allowing real time disease monitoring especially in advanced stages of cancer, but their analysis is technically challenging. OBJECTIVE: We aimed to demonstrate the feasibility of two different technical approaches to detect the BRAFV600E mutation in the liquid biopsy of 20 metastatic melanoma...
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