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Extracellular vesicle DNA from human melanoma tissues contains cancer-specific mutations

1 Dec 2022

Abstract excerpt

Liquid biopsies are promising tools for early diagnosis and residual disease monitoring in patients with cancer, and circulating tumor DNA isolated from plasma has been extensively studied as it has been shown to contain tumor-specific mutations. Extracellular vesicles (EVs) present in tumor tissues carry tumor-derived molecules such as proteins and nucleic acids, and thus EVs can potentially represent a source...

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PMID: 36531960
DOI: 10.3389/fcell.2022.1028854

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