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Article

Clinical application of circulating tumor DNA in metastatic cancers.

Expert review of molecular diagnostics - 1 Jan 2000

Raei Negin, Safaralizadeh Reza, Latifi-Navid Saeid

Abstract excerpt

INTRODUCTION: Advances in genomics have facilitated the application of cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) in phase II and phase III clinical trials. The various mutations of cfDNA/ctDNA have been correlated with clinical features. Advances in next-generation sequencing (NGS) and digital droplet PCR have paved the way for identifying cfDNA/ctDNA mutations. AREAS COVERED: Herein, the biology of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37797209
DOI: 10.1080/14737159.2023.2268008

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