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Article

Scn1a dysfunction alters behavior but not the effect of stress on seizure response.

Genes, brain, and behavior - 1 Mar 2016

Sawyer N T, Helvig A W, Makinson C D, Decker M J, Neigh G N, Escayg A

Abstract excerpt

Mutations in the voltage-gated sodium channel gene SCN1A are responsible for a number of epilepsy disorders, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. In addition, dysfunction in SCN1A is increasingly being linked to neuropsychiatric abnormalities, social deficits and cognitive disabilities. We have previously reported that mice heterozygous for the SCN1A R1648H mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypothalamo-Hypophyseal System

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Source

Identifiers

PMID: 26694226
DOI: 10.1111/gbb.12281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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