Article
Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+).
Epilepsia - 1 Apr 2013
Papale Ligia A, Makinson Christopher D, Christopher Ehlen J, Tufik Sergio, Decker Michael J, Paul Ketema N, Escayg Andrew
Abstract excerpt
PURPOSE: Mutations in the voltage-gated sodium channel (VGSC) gene SCN1A are responsible for a number of epilepsy disorders, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. In addition to seizures, patients with SCN1A mutations often experience sleep abnormaliti...
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