Article
Association of Polymorphic Variants of miRNA Processing Genes with Larynx Cancer Risk in a Polish Population.
BioMed research international - 1 Jan 2015
Osuch-Wojcikiewicz Ewa, Bruzgielewicz Antoni, Niemczyk Kazimierz, Sieniawska-Buccella Olga, Nowak Alicja, Walczak Anna, Majsterek Ireneusz
Abstract excerpt
Laryngeal cancer (LC) is one of the most prevalent types of head and neck cancer. An increasing interest has been focused on the role of microRNA (miRNAs) in LC development. The study group consisted of 135 larynx cancer patients and 170 cancer-free individuals. Nine polymorphisms of pre-miRNA processing genes, DROSHA (rs6877842), DGCR8 (rs3757, rs417309, and rs1640299), RAN (rs14035), XPO5 (), DICER1...
