Article
Evaluation of polymorphisms in microRNA biosynthesis genes and risk of laryngeal cancer in the Polish population.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2000
Bruzgielewicz Antoni, Osuch-Wójcikiewicz Ewa, Walczak Anna, Nowak Alicja, Uczkowski Helen, Majsterek Ireneusz
Abstract excerpt
MicroRNAs are the largest group of short regulatory RNAs. They regulate genes participating in many physiological and pathological processes. The role of micro RNAs in cancer development is also considerable. Therefore, the aim of this study was to evaluate the relationship between DROSHA (rs6877842) and DGCR8 (rs417309, rs1640299) gene polymorphisms with risk of occurrence of laryngeal cancer. The study included...
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