Article
Association of NER pathway gene polymorphisms with susceptibility to laryngeal cancer in a Chinese population.
International journal of clinical and experimental pathology - 1 Jan 2015
Sun Yanan, Tan Lijun, Li Huijun, Qin Xiaowei, Liu Jiangtao
Abstract excerpt
We systematically analyzed the association of nine SNPs of seven key NER pathway genes with the development of laryngeal cancer patients, and investigated whether NER pathway polymorphisms could serve as potential biomarkers for laryngeal cancer risk. 271 patients with pathologically proven laryngeal cancer and 271 control subjects were included in our study. Genotyping of ERCC1 rs11615 and rs2298881, ERCC2...
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