Article
Association of variants of miRNA processing genes with cervical precancerous lesion risk in a southern Chinese population.
Bioscience reports - 29 Jun 2018
Huang Shi-Qi, Zhou Zi-Xing, Zheng Shao-Ling, Liu Dan-Dan, Ye Xiao-Hong, Zeng Cheng-Li, Han Ya-Jing, Wen Zi-Hao, Zou Xiao-Qian, Wu Jing, Liu Yu-Mei, Huang Chui-Can, Wang Yao, Yang Guang, Jing Chun-Xia
Abstract excerpt
The miRNA processing genes play essential roles in the biosynthesis of mammalian miRNAs, and their genetic variants are involved in the development of various cancers. Our study aimed to determine the potential association between miRNA processing gene polymorphisms and cervical precancerous lesions. Five single nucleotide polymorphisms (SNPs), including Ran-GTP (RAN) rs14035, exportin-5 (XPO5) rs11077, DICER1...
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