Article
Genetic variation in MicroRNA genes and risk of oral premalignant lesions.
Molecular carcinogenesis - 1 Feb 2010
Clague Jessica, Lippman Scott M, Yang Hushan, Hildebrandt Michelle A T, Ye Yuanqing, Lee J Jack, Wu Xifeng
Abstract excerpt
MicroRNAs (miRNAs) have been reported to play a key role in oncogenesis and, recently, studies have examined the role miRNAs might play in the risk of premalignant lesions. To our knowledge, no study has investigated the association between miRNA polymorphisms and risk of oral premalignant lesions (OPLs). We genotyped 31 single nucleotide polymorphisms (SNPs) among 21 miRNA-related genes in a case-control study...
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