Article
Effect of red blood cell variants on childhood malaria in Mali: a prospective cohort study.
The Lancet. Haematology - 1 Apr 2015
Lopera-Mesa Tatiana M, Doumbia Saibou, Konaté Drissa, Anderson Jennifer M, Doumbouya Mory, Keita Abdoul S, Diakité Seidina A S, Traoré Karim, Krause Michael A, Diouf Ababacar, Moretz Samuel E, Tullo Gregory S, Miura Kazutoyo, Gu Wenjuan, Fay Michael P, Taylor Steve M, Long Carole A, Diakité Mahamadou, Fairhurst Rick M
Abstract excerpt
BACKGROUND: Red blood cell variants protect African children from severe falciparum malaria. However, their individual and interactive effects on mild disease and parasite density, and their modification by age-dependent immunity, are poorly understood. In this study, we address these knowledge gaps in a prospective cohort study of malaria risk and Plasmodium falciparum densities in Malian children. METHODS: The...
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