Article
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya.
BMC infectious diseases - 7 Apr 2021
Kosiyo Paul, Otieno Walter, Gitaka Jesse, Munde Elly O, Ouma Collins
Abstract excerpt
BACKGROUND: In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these haematological changes during infection. However, the contributions of the carriage of different HBB genotypes on these changes remain largely unknown. METHODOLOGY: In this cross-sectional...
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