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Article

Association between haematological parameters and sickle cell genotypes in children with Plasmodium falciparum malaria resident in Kisumu County in Western Kenya.

BMC infectious diseases - 25 Nov 2020

Kosiyo Paul, Otieno Walter, Gitaka Jesse, Munde Elly O, Ouma Collins

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such as western Kenya. Carriage of different sickle cell genotypes may influence haematological parameter during malaria. Children resident in malaria holoendemic regions suffer more from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33238928
DOI: 10.1186/s12879-020-05625-z
PMCID: PMC7690073

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