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Article

Mannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study.

Respiratory research - 18 Dec 2015

Mandal Jyotshna, Malla Bijaya, Steffensen Rudi, Costa Luigi, Egli Adrian, Trendelenburg Marten, Blasi Francesco, Kostikas Kostantinos, Welte Tobias, Torres Antoni, Louis Renaud, Boersma Wim, Milenkovic Branislava, Aerts Joachim, Rohde Gernot G U, Lacoma Alicia, Rentsch Katharina, Roth Michael, Tamm Michael, Stolz Daiana

Abstract excerpt

BACKGROUND: Functional deficiency of mannose-binding lectin (MBL) may contribute to the pathogenesis of chronic obstructive pulmonary disease. We hypothesized that specific MBL2 gene polymorphisms and circulating MBL protein levels are associated with clinically relevant outcomes in the Predicting Outcome using systemic Markers In Severe Exacerbations of COPD PROMISE-COPD cohort. METHODS: We followed 277 patients...

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Source

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Identifiers

PMID: 26684757
DOI: 10.1186/s12931-015-0306-3
PMCID: PMC4750539

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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