Article
Mannose-binding lectin genotype and serum levels in patients with chronic and allergic pulmonary aspergillosis.
International journal of immunogenetics - 1 Jun 2012
Harrison E, Singh A, Morris J, Smith N L, Fraczek M G, Moore C B, Denning D W
Abstract excerpt
Several studies suggest mannose-binding lectin (MBL) deficiency is associated with various manifestations of aspergillosis. MBL serum levels and function are genetically determined, but levels rise during inflammation. We address the relative frequency of deficient genotypes, the relationship between serum level and genotype and both age and disease manifestations in patients with chronic pulmonary (CPA) and...
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