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Article

Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution.

The Journal of allergy and clinical immunology - 1 Mar 2016

Somineni Hari K, Zhang Xue, Biagini Myers Jocelyn M, Kovacic Melinda Butsch, Ulm Ashley, Jurcak Noelle, Ryan Patrick H, Khurana Hershey Gurjit K, Ji Hong

Abstract excerpt

BACKGROUND: Asthma is a complex disorder influenced by genetics and the environment. Recent findings have linked abnormal DNA methylation in T cells with asthma; however, the potential dysregulation of methylation in airway epithelial cells is unknown. Studies of mouse models of asthma have observed greater levels of 5-hydroxymethylcytosine (5-hmC) and ten-eleven translocation 1 (TET1) expression in lungs. TET...

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Source

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Identifiers

PMID: 26684294
DOI: 10.1016/j.jaci.2015.10.021
PMCID: PMC4783231

Genes

TET1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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