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Article

Nasal DNA Methylation is Associated with Childhood Asthma

25 Apr 2018

Abstract excerpt

AIM: We aim to study DNA methylation (DNAm) variations associated with childhood asthma. METHODS: Nasal DNAm was compared between sibling pairs discordant for asthma, 29 sib pairs for genome-wide association studies and 54 sib pairs for verification by pyrosequencing. Associations of methylation with asthma symptoms, allergy and environmental exposures were evaluated. In vitro experiments and functional genomic...

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PMID: 29692198
DOI: 10.2217/epi-2017-0127

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