Article

TET1 Protects the Lungs from Diesel Exhaust Particle-Induced Inflammation and Abnormal Function

2026-06-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Rationale</bold> : Diesel exhaust particles (DEP) are a major contributor to air pollution-associated asthma exacerbations, promoting oxidative stress, airway inflammation, and Th17‑skewed immune responses. Although epigenetic mechanisms are increasingly recognized as key modulators of environmental lung disease, the role of the DNA demethylation enzyme TET1 in DEP‑induced airw...

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Literature Corpus work: e40b9ef9-4aa3-5cb6-99d2-8164fc7fb298
DOI: 10.21203/rs.3.rs-9860246/v1

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