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Alterations in DNA methylation and airway hyperreactivity in response toin uteroexposure to environmental tobacco smoke

2 Nov 2015

Abstract excerpt

Growing evidence indicates that prenatal exposure to maternal smoking is a risk factor for the development of asthma in children. However, the effects of prenatal environmental tobacco smoke (ETS) exposure on the genome and lung immune cells are unclear. This study aims to determine whether in utero ETS exposure alters DNA methylation patterns and increases airway hyperreactivity (AHR) and inflammation. Pregnant...

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PMID: 26525176
DOI: 10.3109/08958378.2015.1104402

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