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Article

Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation.

American journal of respiratory and critical care medicine - 1 Sept 2009

Breton Carrie V, Byun Hyang-Min, Wenten Made, Pan Fei, Yang Allen, Gilliland Frank D

Abstract excerpt

RATIONALE: Prenatal exposure to tobacco smoke increases the risk for diseases later in the child's life that may be mediated through alterations in DNA methylation. OBJECTIVES: To demonstrate that differences in DNA methylation patterns occur in children exposed to tobacco smoke and that variation in detoxification genes may alter these associations. METHODS: Methylation of DNA repetitive elements, LINE1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19498054
DOI: 10.1164/rccm.200901-0135OC
PMCID: PMC2742762

Genes

AXL
GSTM1
GSTP1
PTPRO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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