Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner

18 Dec 2015

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to TGF-β signaling in diseases
Share to Ubiquitin and proteasome pathways

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26679521
DOI: 10.1038/cdd.2015.152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated mannerPMID 26679521Read ↗

The Post-translational Modifications of Smurf2 in TGF-β SignalingSemantic proximity Read ↗

Smurfs in Protein Homeostasis, Signaling, and CancerSemantic proximity Read ↗

A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Semantic proximity Read ↗

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation.Semantic proximity Read ↗

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.Semantic proximity Read ↗

Ubiquitination of Smad2 by Smurf1 inhibits endothelial-to-mesenchymal transition in human coronary artery endothelial cellsSemantic proximity Read ↗

Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasisSemantic proximity Read ↗

SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stabilitySemantic proximity Read ↗

Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain.Semantic proximity Read ↗

Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and InvasivenessSemantic proximity Read ↗

SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stabilitySemantic proximity Read ↗

Unboxing the network among long non-coding RNAs and TGF-β signaling in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.