Article
[TET proteins and epigenetic modifications in cancers].
Postepy higieny i medycyny doswiadczalnej (Online) - 16 Dec 2015
Ciesielski Piotr, Jóźwiak Paweł, Krześlak Anna
Abstract excerpt
Epigenetic modifications, including DNA methylation and histone modifications, are involved in regulation of gene expression, and alterations in these modifications are implicated in cancer onset and progression. The specific pattern of DNA methylation depends on the balance between methylation and demethylation processes. Recent studies have shown that TET proteins play a key role in DNA demethylation. TET...
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