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Article

TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays.

Scientific reports - 16 Dec 2015

Lin Ching-Hung, Chen I-Chiun, Huang Chiun-Sheng, Hu Fu-Chang, Kuo Wen-Hung, Kuo Kuan-Ting, Wang Chung-Chieh, Wu Pei-Fang, Chang Dwan-Ying, Wang Ming-Yang, Chang Chin-Hao, Chen Wei-Wu, Lu Yen-Shen, Cheng Ann-Lii

Abstract excerpt

IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients diagnosed with stage I-III breast cancer at National Taiwan University Hospital (the NTUH cohort). We obtained...

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Identifiers

PMID: 26671300
DOI: 10.1038/srep17879
PMCID: PMC4680865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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