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Article

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.

Cell stem cell - 4 Feb 2016

Boonsanay Verawan, Zhang Ting, Georgieva Angelina, Kostin Sawa, Qi Hui, Yuan Xuejun, Zhou Yonggang, Braun Thomas

Abstract excerpt

Skeletal muscle stem cells (MuSCs) are required for regeneration of adult muscle following injury, a response that demands activation of mainly quiescent MuSCs. Despite the need for dynamic regulation of MuSC quiescence, relatively little is known about the determinants of this property. Here, we show that Suv4-20h1, an H4K20 dimethyltransferase, controls MuSC quiescence by promoting formation of facultative...

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Identifiers

PMID: 26669898
DOI: 10.1016/j.stem.2015.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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