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Article

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

Journal of molecular cell biology - 1 Oct 2013

Neguembor Maria Victoria, Xynos Alexandros, Onorati Maria Cristina, Caccia Roberta, Bortolanza Sergia, Godio Cristina, Pistoni Mariaelena, Corona Davide F, Schotta Gunnar, Gabellini Davide

Abstract excerpt

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant myopathy with a strong epigenetic component. It is associated with deletion of a macrosatellite repeat leading to over-expression of the nearby genes. Among them, we focused on FSHD region gene 1 (FRG1) since its over-expressi...

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Identifiers

PMID: 23720823
DOI: 10.1093/jmcb/mjt018

Genes

FRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23720823-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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